Leytens, Alexandre |  Benitez-Fernandez, R...... -  《Autophagy》 - 2025,21(2) - 460～475 - 共16页

摘要：Macroautophagy/autophagy is a constitutively active catabolic lysosomal degradation pathway, often found dysregulated in human diseases. It is often considered to act in a cytoprotective manner and is...

关键词： ER-phagy |  mass spectrometry |  mitophagy |  parallel reaction monitoring |  reticulophagy |  selective autophagy receptors

Benitez-Fernandez, R... |  Josa-Prado, Fernando... -  《cns neuroscience & therapeutics》 - 2024,30(1) - 共12页

摘要：Aims: Multiple sclerosis (MS) is a chronic neurological disease that currently lacks effective curative treatments. There is a need to find effective therapies, especially to reverse the progressive d...

关键词： LRRK2 inhibitors |  multiple sclerosis |  remyelinating agents |  DIFFERENTIATION |  REMYELINATION |  MUTATIONS |  DISCOVERY |  POTENT |  BRAIN

Benitez-Fernandez, R... |  Gil, Carmen... -  《international journal of molecular sciences》 - 2022,23(22) - 共12页

摘要：Multiple sclerosis (MS) is a chronic, inflammatory, autoimmune and degenerative disease with axonal damage and demyelination as its main features. Its dual neurological and autoimmune nature makes it ...

关键词： multiple sclerosis |  PDE7 |  GSK beta |  remyelination |  TMEV-IDD |  PPMS |  THEILERS VIRUS-INFECTION |  PHOSPHODIESTERASE 7 |  MURINE MODEL |  CELLS...

Garcia, Carlos Jimen... |  Ignacio Jimenez-Loyg...... -  《investigative ophthalmology & visual science》 - 2024,65(7) - 共3页