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1. The multifaceted nature of HIV tissue reservoirs NSTL国家科技图书文献中心

Banga, Riddhima | Perreau, Matthieu - 《Current opinion in HIV and AIDS》 - 2024,19(3) - 116～123 - 共8页

摘要：Purpose of reviewTo underline the complexity and the heterogeneity of the HIV reservoir.Recent findingsWhile lymphoid tissues (spleen, lymph nodes, gut-associated lymphoid tissue) harbor specific subs...

关键词： compartmentalization | dendritic cells | HIV persistence | HIV reservoir | HIV transcription | lymph node | replication competent HIV | T-follicular helper cells | tissue HIV reservoir | CD4(+) T-CELLS...

2. Lymph node dendritic cells harbor inducible replication-competent HIV despite years of suppressive ART NSTL国家科技图书文献中心

Banga, Riddhima | Procopio, Francesco ...... - 《Cell Host & Microbe》 - 2023,31(10) - 1714～+ - 共28页

摘要：Although gut and lymph node (LN) memory CD4 T cells represent major HIV and simian immunodeficiency virus (SIV) tissue reservoirs, the study of the role of dendritic cells (DCs) in HIV persistence has...

关键词： HELPER T-CELLS | INFECTION | PERSISTENCE | RESERVOIR | TISSUE | ALIGNMENT | SAMHD1 | MACROPHAGES | ACTIVATION | RESISTANCE

3. Elite and posttreatment controllers, two facets of HIV control SCIE Web of Science核心 NSTL国家科技图书文献中心

Mastrangelo, Andrea | Banga, Riddhima ... - 《Current opinion in HIV and AIDS》 - 2022,17(5) - 325～332 - 共8页

摘要：Purpose of review The quest for HIV-1 cure could take advantage of the study of rare individuals that control viral replication spontaneously (elite controllers) or after an initial course of antiretr...

关键词： elite controllers | HIV-1 immune response | HIV-1 reservoir | posttreatment controllers | HUMAN-IMMUNODEFICIENCY-VIRUS | CD4(+) T-CELLS | HLA CLASS-I | ANTIRETROVIRAL THERAPY | TREATMENT INTERRUPTION | NATURAL-HISTORY...

4. Blood and Lymph Node Dissemination of Clonal Genome-Intact Human Immunodeficiency Virus 1 DNA Sequences During Suppressive Antiretroviral Therapy SCIE Web of Science核心 SCOPUS Scopus数据库 NSTL国家科技图书文献中心

Kuo, Hsiao-Hsuan | Banga, Riddhima ... - 《The Journal of Infectious Diseases》 - 2020,222(4) - 655～660 - 共6页

摘要：The majority of cells with latent human immunodeficiency virus 1 infection are located in lymphoid tissues that are difficult to access. In the current study, we used single-genome near-full-length pr...

关键词： HIV-1 | reservoir | Lymph node | proviral sequencing | CD4 T cells

5. Current approaches to assess HIV-1 persistence NSTL国家科技图书文献中心

Banga, Riddhima | Procopio, Francesco ...... - 《Current opinion in HIV and AIDS》 - 2016,11(4) - 424～431 - 共8页

摘要：Purpose of review

关键词： integrated HIV DNA | quantitative viral outgrowth assay | tat/rev-induced limiting dilution analysis

6. TLR3 agonist and CD40-targeting vaccination induces immune responses and reduces HIV-1 reservoirs SCIE Web of Science核心 SCOPUS Scopus数据库 NSTL国家科技图书文献中心

Cheng, Liang | Wang, Qi ... - 《The Journal of Clinical Investigation: The Official Journal of the American Society for Clinical Investigation》 - 2018,128(10) - 4387～4396 - 共10页

摘要：Activation of HIV-1 reservoirs and induction of anti-HIV-1 T cells are critical to control HIV-1 rebound after combined antiretroviral therapy (cART). Here we evaluated in humanized mice (hu-mice) wit...

7. Targeted Immune Interventions for an HIV-1 Cure SCOPUS Scopus数据库 SCIE Web of Science核心 NSTL国家科技图书文献中心

Perreau, Matthieu | Banga, Riddhima ... - 《Trends in molecular medicine》 - 2017,23(10) - 945～961 - 共17页

摘要：Combination antiretroviral therapy (cART) induces durable suppression of virus replication but is unable to eradicate HIV. Invariably, virus rebound follows treatment interruption and life-long cART i...

8. In Vitro Reactivation of Replication-Competent and Infectious HIV-1 by Histone Deacetylase Inhibitors SCOPUS Scopus数据库 SCIE Web of Science核心 NSTL国家科技图书文献中心

Banga, Riddhima | Procopio, Francesco ...... - 《Journal of Virology》 - 2016,90(4) - 1858～1871 - 共14页

摘要：The existence of long-lived HIV-1-infected resting memory CD4 T cells is thought to be the primary obstacle to HIV-1 eradication. In the search for novel therapeutic approaches that may reverse HIV-1 ...

9. PD-1(+) and follicular helper T cells are responsible for persistent HIV-1 transcription in treated aviremic individuals SCIE Web of Science核心 SCOPUS Scopus数据库 NSTL国家科技图书文献中心

Banga, Riddhima | Procopio, Francesco ...... - 《Nature medicine》 - 2016,22(7) - 754～761 - 共8页

摘要：The mechanisms responsible for the persistence of HIV-1 after many years of suppressive antiretroviral therapy (ART) have been only partially elucidated. Most of the studies investigating HIV-1 persis...

10. Host Molecule Incorporation into HIV Virions, Potential Influences in HIV Pathogenesis

Munoz, Olivia | Banga, Riddhima ... - 《Viruses》 - 2022,14(11) - 共13页

摘要：During the last phase of HIV viral production, nascent HIV virions acquire a fraction of the cellular lipid membrane to create the external lipid envelope, a process by which cellular proteins present...

关键词： HIV | replication cycle | protein incorporation | pathogenesis | IMMUNODEFICIENCY-VIRUS TYPE-1 | T-CELL DEPLETION | HLA CLASS-II | ENVELOPE GLYCOPROTEINS | ADHESION MOLECULES | DENDRITIC CELLS...

摘要：Purpose of reviewTo underline the complexity and the heterogeneity of the HIV reservoir.Recent findingsWhile lymphoid tissues (spleen, lymph nodes, gut-associated lymphoid tissue) harbor specific subs...

关键词： compartmentalization | dendritic cells | HIV persistence | HIV reservoir | HIV transcription | lymph node | replication competent HIV | T-follicular helper cells | tissue HIV reservoir | CD4(+) T-CELLS...

摘要：Although gut and lymph node (LN) memory CD4 T cells represent major HIV and simian immunodeficiency virus (SIV) tissue reservoirs, the study of the role of dendritic cells (DCs) in HIV persistence has...

关键词： HELPER T-CELLS | INFECTION | PERSISTENCE | RESERVOIR | TISSUE | ALIGNMENT | SAMHD1 | MACROPHAGES | ACTIVATION | RESISTANCE

摘要：Purpose of review The quest for HIV-1 cure could take advantage of the study of rare individuals that control viral replication spontaneously (elite controllers) or after an initial course of antiretr...

关键词： elite controllers | HIV-1 immune response | HIV-1 reservoir | posttreatment controllers | HUMAN-IMMUNODEFICIENCY-VIRUS | CD4(+) T-CELLS | HLA CLASS-I | ANTIRETROVIRAL THERAPY | TREATMENT INTERRUPTION | NATURAL-HISTORY...

摘要：The majority of cells with latent human immunodeficiency virus 1 infection are located in lymphoid tissues that are difficult to access. In the current study, we used single-genome near-full-length pr...

关键词： HIV-1 | reservoir | Lymph node | proviral sequencing | CD4 T cells

摘要：Purpose of review

关键词： integrated HIV DNA | quantitative viral outgrowth assay | tat/rev-induced limiting dilution analysis

摘要：Activation of HIV-1 reservoirs and induction of anti-HIV-1 T cells are critical to control HIV-1 rebound after combined antiretroviral therapy (cART). Here we evaluated in humanized mice (hu-mice) wit...

摘要：Combination antiretroviral therapy (cART) induces durable suppression of virus replication but is unable to eradicate HIV. Invariably, virus rebound follows treatment interruption and life-long cART i...

摘要：The existence of long-lived HIV-1-infected resting memory CD4 T cells is thought to be the primary obstacle to HIV-1 eradication. In the search for novel therapeutic approaches that may reverse HIV-1 ...

摘要：The mechanisms responsible for the persistence of HIV-1 after many years of suppressive antiretroviral therapy (ART) have been only partially elucidated. Most of the studies investigating HIV-1 persis...

摘要：During the last phase of HIV viral production, nascent HIV virions acquire a fraction of the cellular lipid membrane to create the external lipid envelope, a process by which cellular proteins present...

关键词： HIV | replication cycle | protein incorporation | pathogenesis | IMMUNODEFICIENCY-VIRUS TYPE-1 | T-CELL DEPLETION | HLA CLASS-II | ENVELOPE GLYCOPROTEINS | ADHESION MOLECULES | DENDRITIC CELLS...

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