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1. MLH1 gene promoter methylation status partially overlaps with CpG methylator phenotype (CIMP) in colorectal adenocarcinoma NSTL国家科技图书文献中心

Ceccon, Carlotta |  Borga, Chiara... -  《Pathology Research and Practice》 - 2025,266 - 155786~155786 - 共8页

摘要:Background RAS/BRAF mutations, mismatch DNA repair complex deficiency (MMRd)/microsatellite instability (MSI), and CpG methylator phenotype (CIMP) are key molecular actors in colorectal carcinogenesis...
关键词: Colorectal cancer |  MLH1 |  CIMP |  BRAF |  Molecular profiling |  MMR

2. Are IDH1 R132 Mutations Associated With Poor Prognosis in Patients With Chondrosarcoma of the Bone? NSTL国家科技图书文献中心

Trovarelli, Giulia |  Sbaraglia, Marta... -  《Clinical Orthopaedics and Related Research》 - 2024,482(6) - 947~956 - 共10页 - 被引量:4

摘要:Background Because chondrosarcomas vary widely in their behavior, and because anticipating their behavior based on histology alone can be challenging, genetic markers represent an appealing area of in...
关键词: ISOCITRATE DEHYDROGENASE 1 |  ONCOMETABOLITE 2-HYDROXYGLUTARATE |  DEDIFFERENTIATED CHONDROSARCOMA |  SURVIVAL |  SARCOMA |  TUMOR

3. miR-24-3p regulates CDX2 during intestinalization of cardiac-type epithelium in a human model of Barrett's esophagus SCOPUS Scopus数据库 SCIE Web of Science核心 NSTL国家科技图书文献中心

Gil-Gomez, Gabriel |  Fassan, Matteo... -  《Diseases of the esophagus: official journal of the International Society for Diseases of the Esophagus》 - 2021,34(7) - 共13页

摘要:Background: Cardiac-type epithelium has been proposed as the precursor of intestinal metaplasia in the development of Barrett's esophagus. Dysregulation of microRNAs (miRNAs) and their effects on CDX2...
关键词: Barrett's esophagus |  cardiac-type epithelium |  CDX2 transcription factor |  intestinal metaplasia |  microRNAs

4. Molecular profiling of appendiceal serrated lesions, polyps and mucinous neoplasms: a single-centre experience SCIE Web of Science核心 SCOPUS Scopus数据库 NSTL国家科技图书文献中心

Munari, Giada |  Businello, Gianluca... -  《Journal of Cancer Research and Clinical Oncology》 - 2021,147(7) - 1897~1904 - 共8页 - 被引量:8

摘要:Purpose Non-neuroendocrine neoplasms of the appendix are a phenotypically heterogeneous group of lesions; a comprehensive molecular characterization of these tumors is still lacking. Methods A total o...
关键词: Appendiceal neoplasms |  Serrated lesions |  Molecular pathology |  Biomarkers |  Pseudomyxoma peritonei

5. mTOR pathway and somatostatin receptors expression intratumor-heterogeneity in ileal NETs NSTL国家科技图书文献中心

Borga, Chiara |  Dal Pozzo, Carlo Alb...... -  《Endocrine-related cancer》 - 2021,28(7) - 449~456 - 共8页 - 被引量:2

摘要:The knowledge of the molecular landscape of ileal neuroendocrine tumors (NETs) is affected by the lack of systematic studies investigating intra-tumoral heterogeneity. In this study, intra-tumoral het...
关键词: neuroendocrine neoplasms |  immunohistochemistry |  heterogeneity |  gastrointestinal tumors

6. Synaptophysin expression in (V600EBRAF-)mutated advanced colorectal cancers identifies a new subgroup of tumours with worse prognosis SCOPUS Scopus数据库 SCIE Web of Science核心 NSTL国家科技图书文献中心

Fassan, Matteo |  Milione, Massimo... -  《European journal of cancer: official journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)》 - 2021,146 - 145~154 - 共10页 - 被引量:5

摘要:Background: Neuroendocrine differentiation has been extensively associated with worse prognosis and to mechanisms of therapy resistance in several epithelial cancers. A high prevalence of neuroendocri...
关键词: Colorectal cancer |  Synaptophysin |  (V600E)BRAF |  Immunohistochemistry |  Neuroendocrine |  Prognostic markers

7. Direct Effect of Septic Plasma in Human Cell Lines Viability SCIE Web of Science核心 SCOPUS Scopus数据库 NSTL国家科技图书文献中心

Virzi, Grazia Maria |  Borga, Chiara... -  《Blood purification》 - 2019,47(1/3) - 270~276 - 共7页

摘要:Background: Sepsis is a life-threatening condition often associated with a high incidence of multiple organs injury. Several papers suggested the immune response by itself, with the production of humo...
关键词: Sepsis |  Humoral mediators |  Apoptosis |  Intrinsic and extrinsic pathways

8. TET1 promotes growth of T-cell acute lymphoblastic leukemia and can be antagonized via PARP inhibition SCOPUS Scopus数据库 SCIE Web of Science核心 NSTL国家科技图书文献中心

Bamezai, Shiva |  Demir, Deniz... -  《Leukemia: Official journal of the Leukemia Society of America, Leukemia Research Fund, U.K》 - 2021,35(2) - 389~403 - 共15页 - 被引量:17

摘要:T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological cancer characterized by skewed epigenetic patterns, raising the possibility of therapeutically targeting epigenetic factors i...
检索条件作者:Borga, Chiara
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