Johnson, Matthew G. |  Pokorny, Lisa... -  《Systematic Biology》 - 2019,68(4) - 594～606 - 共13页 - 被引量：278

摘要：Sequencing of target-enriched libraries is an efficient and cost-effective method for obtaining DNA sequence data from hundreds of nuclear loci for phylogeny reconstruction. Much of the cost of develo...

关键词： Angiosperms |  Hyb-Seq |  k-means clustering |  k-medoids clustering |  machine learning |  nuclear genes |  phylogenomics |  sequence capture |  target enrichment

Henn, Brenna M. |  Botigue, Laura R.... -  《Proceedings of the National Academy of Sciences of the United States of America.》 - 2016,113(4) - E440～E449 - 共10页 - 被引量：126

摘要：The Out-of-Africa (OOA) dispersal similar to 50,000 y ago is characterized by a series of founder events as modern humans expanded into multiple continents. Population genetics theory predicts an incr...

关键词： mutation |  founder effect |  range expansion |  expansion load |  purifying selection

Scott, Michael F. |  Botigue, Laura R.... -  《Nature Plants》 - 2019,5(11) - 1120～+ - 共14页 - 被引量：30

摘要：Tetraploid emmer wheat (Triticum turgidum ssp. dicoccon) is a progenitor of the world's most widely grown crop, hexaploid bread wheat (Triticum aestivum), as well as the direct ancestor of tetraploid ...

Henn, Brenna M. |  Botigue, Laura R.... -  《Nature reviews. Genetics》 - 2015,16(6) - 333～343 - 共11页 - 被引量：138

摘要：Next-generation sequencing technology has facilitated the discovery of millions of genetic variants in human genomes. A sizeable fraction of these variants are predicted to be deleterious. Here, we re...

Botigue, Laura R. |  Henn, Brenna M.... -  《American Journal of Physical Anthropology》 - 2015,(Suppl.60) - 90～91 - 共2页

Botigue, Laura R. |  Song, Shiya... -  《Nature Communications》 - 2017,8 - 共11页

摘要：Europe has played a major role in dog evolution, harbouring the oldest uncontested Palaeolithic remains and having been the centre of modern dog breed creation. Here we sequence the genomes of an Earl...

关键词： GENETIC-STRUCTURE |  COPY NUMBER |  ADMIXTURE |  DOMESTICATION |  HISTORY |  ORIGIN |  PATTERNS |  INFERENCE |  DAMAGE

Haber, Marc |  Gauguier, Dominique... -  《plos genetics》 - 2013,9(2) - 共8页 - 被引量：49

摘要：The Levant is a region in the Near East with an impressive record of continuous human existence and major cultural developments since the Paleolithic period. Genetic and archeological studies present ...

关键词： HAPLOTYPE |  ADMIXTURE |  ANCESTRY

Sanchez-Quinto, Fede... |  Botigue, Laura R.... -  《plos one》 - 2012,7(10) - 共6页 - 被引量：38

摘要：One of the main findings derived from the analysis of the Neandertal genome was the evidence for admixture between Neandertals and non-African modern humans. An alternative scenario is that the ancest...

关键词： EUROPE |  JACKKNIFE |  ANCESTRY |  ORIGINS |  HISTORY |  ASIA

Henn, Brenna M. |  Botigue, Laura R.... -  《plos genetics》 - 2012,8(1) - 共11页 - 被引量：182

摘要：North African populations are distinct from sub-Saharan Africans based on cultural, linguistic, and phenotypic attributes; however, the time and the extent of genetic divergence between populations no...

关键词： WIDE PATTERNS |  POPULATION-STRUCTURE |  PARKINSONS-DISEASE |  GENETIC-VARIATION |  DNA VARIATION |  ADMIXTURE |  ASSOCIATION |  ORIGIN