NSTL国家科技图书文献中心

1. The lateral septum returns to the center stage of brain reward NSTL国家科技图书文献中心

Chow, Jonathan J. | Madangopal, Rajtarun ... - 《Neuron》 - 2024,112(16) - 2666～2668 - 共3页

摘要：In this issue of Neuron, , Chen et al.1 1 found that lateral septum Esr1-expressing cells respond to both non-drug and drug rewards. Mice will lever press for optogenetic stimulation of these neurons,...

关键词： STIMULATION REWARD

2. A rat model of operant negative reinforcement in opioid-dependent males and females NSTL国家科技图书文献中心

Chow, Jonathan J. | Pitts, Kayla M.... - 《Psychopharmacology》 - 2024,241(9) - 1791～1813 - 共23页

摘要：Rationale and objectiveAvoidance of opioid withdrawal plays a key role in human opioid addiction. Here, we present a procedure for studying operant negative reinforcement in rats that was inspired by ...

关键词： Avoidance learning | Opioid dependence | Methadone | Negative reinforcement | Opioid | Dependence | Opioid withdrawal | ACTIVE-AVOIDANCE | CONDITIONED FEAR | MORPHINE...

3. Effect of Selective Lesions of Nucleus Accumbens ?-Opioid Receptor-Expressing Cells on Heroin Self-Administration in Male and Female Rats: A Study with Novel Oprm1-Cre Knock-in Rats NSTL国家科技图书文献中心

Bossert, Jennifer M. | Mejias-Aponte, Carlo...... - 《The Journal of neuroscience :》 - 2023,43(10) - 1692～1713 - 共22页 - 被引量：5

摘要：The brain mu-opioid receptor (MOR) is critical for the analgesic, rewarding, and addictive effects of opioid drugs. However, in rat models of opioid-related behaviors, the circuit mechanisms of MOR-ex...

关键词： mu opioid receptor | knockin | CRISPR | heroin self-administration | pain | caspase 3 lesion | PRIMING-INDUCED REINSTATEMENT | CONTEXT-INDUCED RELAPSE | DRUG RELAPSE | ANTAGONIST TREATMENT...

4. The Protective Effect of Social Reward on Opioid and Psychostimulant Reward and Relapse: Behavior, Pharmacology, and Brain Regions SCIE Web of Science核心 NSTL国家科技图书文献中心

Venniro, Marco | Marino, Rosa A. M.... - 《The Journal of neuroscience :》 - 2022,42(50) - 9298～9314 - 共17页 - 被引量：9

摘要：Until recently, most modern neuroscience research on addiction using animal models did not incorporate manipulations of social factors. Social factors play a critical role in human addiction: social i...

关键词： | addiction | animal models | craving | opioids | psychostimulants | social behavior | CONDITIONED PLACE PREFERENCE | AMPHETAMINE CROSS-SENSITIZATION | NEURAL PLASTICITY MECHANISMS...

5. Remifentanil-food choice follows predictions of relative subjective value SCIE Web of Science核心 SSCI 社会科学引文索引 SCOPUS Scopus数据库 NSTL国家科技图书文献中心

Chow, Jonathan J. | Beckmann, Joshua S. - 《Drug and alcohol dependence》 - 2021,218 - 共9页 - 被引量：11

摘要：Background: Preclinical studies into drug vs. nondrug choice have emerged to better model and investigate the neurobehavioral mechanisms underlying drug preference. Current literature has suggested th...

关键词： Remifentanil | Choice | Matching | Magnitude | Rat

6. Neuronal activity associated with cocaine preference: Effects of differential cocaine intake SCIE Web of Science核心 SCOPUS Scopus数据库 NSTL国家科技图书文献中心

Chow, Jonathan J. | Hofford, Rebecca S.... - 《Neuropharmacology》 - 2021,184 - 共8页 - 被引量：3

摘要：Differences in overall cocaine intake can directly affect neuroadaptations, and this relationship can make it difficult to interpret neurobiological changes seen in drug-choice studies, since drug int...

关键词： Cocaine | Choice | Decision-making | Immunohistochemistry | In situ hybridization

7. Presence of a social peer enhances acquisition of remifentanil self-administration in male rats SCIE Web of Science核心 SCOPUS Scopus数据库 SSCI 社会科学引文索引 NSTL国家科技图书文献中心

Hofford, Rebecca S. | Bond, Paige N.... - 《Drug and alcohol dependence》 - 2020,213 - 共10页 - 被引量：4

摘要：Background: Social peers influence human drug use at every stage of addiction. Using a dual-compartment apparatus that allows for limited social contact, recent work has shown that cocaine self-admini...

关键词： Social | Remifentanil | Self-administration | Peer | Opioid

8. Cocaine-associated decision-making: Toward isolating preference SCOPUS Scopus数据库 SCIE Web of Science核心 NSTL国家科技图书文献中心

Beckmann, Joshua S. | Chow, Jonathan J.... - 《Neuropharmacology》 - 2019,153 - 142～152 - 共11页 - 被引量：11

摘要：Ever-increasing evidence suggests that substance use disorder is mediated by decision-making processes, and as such, providing nondrug alternatives can shift maladaptive preferences away from drug rei...

关键词： Decision-making | Cocaine | Choice | Economic substitution

9. NMDA receptor blockade specifically impedes the acquisition of incentive salience attribution SCOPUS Scopus数据库 SCIE Web of Science核心 NSTL国家科技图书文献中心

Chow, Jonathan J. | Beckmann, Joshua S. - 《Behavioural Brain Research: An International Journal》 - 2018,338 - 40～46 - 共7页 - 被引量：4

摘要：Glutamatergic signaling plays an important role in learning and memory. Using Pavlovian conditioned approach procedures, the mechanisms that drive stimulus-reward learning and memory have been investi...

关键词： Incentive salience | Glutamate | MK-801 | Sign-tracking | Goal-tracking

10. Suboptimal choice in rats: Incentive salience attribution promotes maladaptive decision-making SCIE Web of Science核心 SCOPUS Scopus数据库 NSTL国家科技图书文献中心

Chow, Jonathan J. | Smith, Aaron P.... - 《Behavioural Brain Research: An International Journal》 - 2017,320 - 244～254 - 共11页 - 被引量：38

摘要：Stimuli that are more predictive of subsequent reward also function as better conditioned reinforcers. Moreover, stimuli attributed with incentive salience function as more robust conditioned reinforc...