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1. Safety, pharmacokinetics and pharmacodynamics of multiple‐dose noiiglutide (SHR20004), a novel GLP‐1 receptor agonist, in Chinese obese subjects without diabetes mellitus NSTL国家科技图书文献中心

Yang Zou |  Fan Jiang... -  《Diabetes, obesity & metabolism.》 - 2025,27(2) - 816~824 - 共9页

摘要:Abstract Aims This study aimed to assess the safety, pharmacokinetics and pharmacodynamics of noiiglutide (SHR20004), a novel glucagon‐like peptide‐1 receptor agonist, in Chinese obese participants wi...
关键词: antiobesity drug |  clinical trial |  GLP‐1 analogue |  obesity therapy |  phase I–II study

2. Effects of temperature on physiology, transcription, and toxin production of the harmful benthic dinoflagellate Gambierdiscus belizeanus NSTL国家科技图书文献中心

Gu J. |  Chan S.S.W.... -  《Marine pollution bulletin》 - 2025,211(Feb.) - 1.1~1.13 - 共13页

摘要:© 2024Benthic dinoflagellates constitute a group of microalgae that inhabit the ocean floor, adhering to substrates such as coral, seagrasses, and sand. Certain species within this group have the pote...
关键词: 44-methylgambierone |  Algal toxins |  Climate change |  Gambierone |  Harmful dinoflagellate blooms |  Transcriptome

3. Advanced line-finite-element for lateral-torsional buckling of beams with torsion and warping restraints NSTL国家科技图书文献中心

Zhang H.-Y. |  Ho G.W.M.... -  《Journal of Constructional Steel Research》 - 2025,224(Jan. Pt.A) - 1.1~1.17 - 共17页

摘要:© 2024 Elsevier LtdSteel beams are susceptible to lateral-torsional buckling (LTB) failure when subjected to bending. Considering the effect of semi-rigid connections, the partial end restraints in to...
关键词: Lateral-torsional buckling |  Line-finite-element |  Partial restraints |  Steel structures |  Warping

4. Global buckling analysis of IFC-protected steel members with irregular sections under fire NSTL国家科技图书文献中心

Li G. |  Gu Z.-Z.... -  《Journal of Constructional Steel Research》 - 2025,224(Jan. Pt.A) - 1.1~1.19 - 共19页

摘要:© 2024 Elsevier LtdIntumescent fire coating (IFC) is currently the major passive protection of steel structures under fire. However, the buckling behavior of IFC-protected steel members with irregular...
关键词: Cross-section analysis |  Finite-element method |  Fire |  Global buckling |  Intumescent fire coating |  Steel structure

5. Low-dose ionizing radiation promotes motor recovery and brain rewiring by resolving inflammatory response after brain injury and stroke NSTL国家科技图书文献中心

Au N.P.B. |  Wu T.... -  《Brain, Behavior, and Immunity》 - 2024,115 - 43~63 - 共21页

摘要:? 2023 Elsevier Inc.Traumatic brain injury (TBI) and stroke share a common pathophysiology that worsens over time due to secondary tissue injury caused by sustained inflammatory response. However, stu...
关键词: Low-dose ionizing radiation |  Microglia polarization |  Photothrombotic stroke |  Traumatic brain injury

6. Associations between epilepsy, respiratory impairment, and minor ECG abnormalities in children NSTL国家科技图书文献中心

Chan S.W. |  Chun A.... -  《Seizure: the journal of the British Epilepsy Association》 - 2024,122 - 39~44 - 共6页

摘要:? 2024 British Epilepsy AssociationObjective: We sought to examine the effects of acute seizures and respiratory derangement on the cardiac electrical properties reflected on the electrocardiogram (EC...
关键词: Cardiac |  ECG |  Epilepsy |  Pediatric |  Respiratory

7. Musculoskeletal crosstalk in chronic obstructive pulmonary disease and comorbidities: Emerging roles and therapeutic potentials NSTL国家科技图书文献中心

Mou K. |  Chan S.M.H.... -  《Pharmacology and Therapeutics: The Journal of the International Encyclopedia of Pharmacology and Therapeutics》 - 2024,257 - 108635~108635 - 共6页

摘要:? 2024 The AuthorsChronic Obstructive Pulmonary Disease (COPD) is a multifaceted respiratory disorder characterized by progressive airflow limitation and systemic implications. It has become increasin...
关键词: Antioxidant |  Exacerbations |  Macrophage polarisation |  Musculoskeletal-lung axis |  Precision medicine |  Pulmonary rehabilitation

8. Intangible maritime heritage protection in Malaysia: The need for a revision of the National Heritage Act of 2005 NSTL国家科技图书文献中心

Nik Hariry N.N. |  Md Hanafiah R.... -  《Marine policy》 - 2024,168(Oct.) - 1.1~1.4 - 共4页

摘要:? 2024 Elsevier LtdMalaysia, as a coastal nation, has an array of maritime cultural heritage artifacts, some of which are submerged beneath the water's surface. Despite the country's previous efforts ...
关键词: Archaeology |  Malaysia |  Maritime |  National Heritage Act of 2005 |  Underwater cultural heritage |  UNESCO

9. Mandibular Advancement vs CPAP for Blood Pressure Reduction in Patients With Obstructive Sleep Apnea NSTL国家科技图书文献中心

Ou Y.-H. |  Colpani J.T.... -  《Journal of the American College of Cardiology》 - 2024,83(18) - 1760~1772 - 共13页

摘要:? 2024 The AuthorsBackground: Hypertension guidelines recommend diagnosis and treatment of obstructive sleep apnea (OSA) in patients with hypertension. The mandibular advancement device (MAD) is an or...
关键词: continuous positive airway pressure |  hypertension |  mandibular advancement device |  noninferiority trial |  obstructive sleep apnea

10. A novel combination of machine learning and intelligent optimization algorithm for modeling and optimization of green ammonia synthesis NSTL国家科技图书文献中心

Deng Z. |  Zhang L.... -  《Energy conversion & management》 - 2024,311(Jul.) - 1.1~1.13 - 共13页

摘要:? 2024 Elsevier LtdGreen ammonia synthesis is an important industrial chemical process, which is widely applied in fields such as fertilizers, petrochemicals and fuel cells. In order to improve green ...
关键词: Ammonia synthesis reactor |  Bald eagle search algorithm |  Green ammonia |  Model interpretation |  Sparse identification
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